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RESEARCH PRODUCT
Orbital apex syndrome affecting head and neck cancer patients: A case series
Alan-roger Santos-silvaMarco-aurelio MontezumaAna-carolina Prado-ribeiroThais-bianca BrandaoAna-claudia LuizMilena-perez Maksubject
MaleLarynxmedicine.medical_specialty03 medical and health sciences0302 clinical medicinePtosisTongueOptic Nerve DiseasesmedicineHumansCranial nerve diseaseGeneral DentistryAgedRetrospective StudiesDiplopiabusiness.industryResearchCranial nervesHead and neck cancerRetrospective cohort studySyndrome030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCranial Nerve DiseasesSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and Neck Neoplasms030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASSurgeryOral Surgerymedicine.symptombusinessdescription
Background Orbital apex syndrome (OAS) is a complex and uncommon disorder that typically damages multiple cranial nerves in association with optic nerve dysfunction. OAS is associated with several different pathologies, however; only a few cases have been reported in association with head and neck cancer (HNC) so far. Material and Methods A case series of HNC patients diagnosed with OAS is described including clinicopathological data, image findings, and disease outcome. Results Ptosis and diplopia were diagnosed in four male patients with mean age of 61.2 years who were undergoing treatment for late-stage carcinomas of the tongue, larynx, and nasopharynx, eventually leading to the diagnosis of OAS. The mean overall survival rate after the diagnosis of OAS was 9.5 months. Conclusions The current study reinforces evidence that OAS indicates poor prognosis and highlights the importance of early diagnosis. Key words:Head and neck cancer, oral cancer, metastasis, orbital apex syndrome, optic neuropathy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-04-01 | Medicina Oral Patología Oral y Cirugia Bucal |