Simultaneous identification of campylobacters and prediction of quinolone resistance by comparative sequence analysis.

6533b82afe1ef96bd128ccd6

RESEARCH PRODUCT

Simultaneous identification of campylobacters and prediction of quinolone resistance by comparative sequence analysis.

C Freytag A. Feddersen Sucharit Bhakdi A. Steitz Matthias Husmann

subject

Microbiology (medical)Silent mutation DNA Bacterial medicine.drug_class Sequence analysis Sequence alignment Biology medicine.disease_cause DNA gyrase Polymerase Chain Reaction law.invention Anti-Infective Agents Species Specificity law medicine Polymerase chain reaction Antibacterial agent Genetics Mutation 4-Quinolones Sequence Homology Amino Acid Campylobacter Drug Resistance Microbial Sequence Analysis DNA Quinolone DNA Topoisomerases Type II DNA Gyrase Sequence Alignment Research Article

description

Comparative sequence analysis of a 30-bp segment in the quinolone resistance-determining region of campylobacters not only allows for the detection of base changes associated with resistance but also is a powerful tool for species identification based on silent mutations.

year	journal	country	edition	language
1997-09-01

https://europepmc.org/articles/PMC229975/

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