6533b82bfe1ef96bd128d542
RESEARCH PRODUCT
Effect of local ischemia on induction of cardiac reentries
Pierre AugerM.-c. GovaereA. BardouDominique Von EuwSoumeya AchourPhilippe DumeeReda Farahsubject
Materials scienceRefractory periodIschemiaDepolarizationMechanicsReentrymedicine.diseaseStandard deviationmedicine.anatomical_structureVentriclemedicineSurface elementDispersion (water waves)Simulationdescription
In this paper, we study the effects of local ischemia on the process of triggering of reentry mechanism. We present computer simulations based on a cellular automata model of the propagation of the depolarizing wave through a ventricular surface element. We simulate a local area of ischemia where effects of refractory period dispersion are investigated. We use a gaussian distribution of the refractory periods characterized by a mean value and a standard deviation. These simulations show that there exist critical conditions necessary to initiate a reentry mechanism invading progressively the whole ventricle.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-10-01 | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society |