6533b82bfe1ef96bd128d658

RESEARCH PRODUCT

Toxicokinetics of xenobiotics in zebrafish—Comparison between tap and river water

Roland NagelUwe Ensenbach

subject

PharmacologybiologyChemistryImmunologyKineticsFresh WaterBioconcentrationbiology.organism_classificationRiver waterXenobioticsStructure-Activity Relationshipchemistry.chemical_compoundTap waterWater SupplyEnvironmental chemistryAnimalsToxicokineticsLindaneXenobioticZebrafishWater Pollutants ChemicalZebrafish

description

Abstract 1. 1. Uptake and elimination of lindane, 3,4-dichloroaniline, phenol and 4-nitrophenol by the zebrafish Brachydanio rerio were investigated in tap water and in water of the river Rhine. 2. 2. The differences in bioconcentration of chemicals between the two water types did not exceed a factor of 2.5. 3. 3. Elimination kinetics were comparable in tap and river water. 4. 4. It can be concluded that water of the river Rhine does not influence the kinetics of the investigated xenobiotics.

https://doi.org/10.1016/0742-8413(91)90120-i