6533b82bfe1ef96bd128d760

RESEARCH PRODUCT

N‐[tert‐Butoxy­carbonyl­glycyl‐(E)‐α,β‐dehydro­phenyl­alanylglycylglycyl‐(E)‐α,β‐dehydro­phenyl­alan­yl]glycine

subject

description

In the mol­ecule of the title hexa­peptide, Boc0–Gly1–ΔEPhe2–Gly3–Gly4–ΔEPhe5–Gly6–OH, C31H36N6O9, there are two overlapping β-turns, one of type II on the ΔEPhe2 (ΔEPhe is isomer E of the α,β-dehydro­phenyl­alanine residue) and Gly3 residues and the second of type III′ on the Gly3 and Gly4 residues. All amino acids in the peptide are linked trans to each other. Three relatively strong intra­molecular N—H⋯O hydrogen bonds stabilize the crystal structure. Two of them, of the 4→1 type, are responsible for two β-turns in the peptide.