6533b82bfe1ef96bd128d8ae

RESEARCH PRODUCT

Genome organization and nucleotide sequence of human papillomavirus type 39

Rolf E. StreeckChristoph Volpers

subject

Genes ViralvirusesMolecular Sequence DataBiologyGenomeHomology (biology)VirusOpen Reading FramesViral ProteinsPapovaviridaechemistry.chemical_compoundSequence Homology Nucleic AcidVirologyHumansCodonPapillomaviridaeGenomic organizationGeneticsBase SequenceNucleic acid sequencevirus diseasesOpen reading framechemistryDNA ViralRNA ViralDNA

description

The 7833-bp nucleotide sequence of human papillomavirus type 39 (HPV39), which is associated with genital intraepithelial neoplasias and invasive carcinomas, has been determined. The genome organization deduced from the sequence shares characteristic features with other genital papillomaviruses. According to sequence comparisons, HPV39 most closely resembles HPV18 and may be a member of a subgroup of genital papillomaviruses distinct from the HPV16/31/33 group. As a novel feature, we report a 1.3-kb open reading frame on the DNA strand which lacks major open reading frames in the other sequenced HPV genomes.

yearjournalcountryeditionlanguage
1991-03-01Virology
https://doi.org/10.1016/0042-6822(91)90518-g