6533b82bfe1ef96bd128def9

RESEARCH PRODUCT

Impact of Various Thermal Doses on the Oxygenation and Blood Flow in Malignant Tumors Upon Localized Hyperthermia

R. ManzPeter VaupelW. Müller-klieserJ. Otte

subject

Tissue temperatureHyperthermiabusiness.industrymedicine.medical_treatmentOxygenationBlood flowTumor Oxygenationmedicine.diseaseRadiation therapyIn vivoAnesthesiamedicinebusinessOxyhemoglobin saturation

description

Hyperthermia exhibits various direct cytocidal effects (Dickson, 1977; Overgaard, 1977; Suit, 1977). During heat treatment in vivo, several indirect mechanisms enhance the direct cell-killing capacity of hyperthermia. Therefore, the effective use of hyperthermia can overcome some of the well-known problems involved in modern radiation therapy at least in some malignant tumors.

https://doi.org/10.1007/978-1-4684-1188-1_56