6533b82bfe1ef96bd128dfc7

RESEARCH PRODUCT

Anion Receptors Based on a Quinoline Backbone

Gerhard RaabeMarkus AlbrechtOlga OsetskaTriyantiStefanie SchiffersThomas WielandKari RissanenLuca Russo

subject

chemistry.chemical_compoundChloroformchemistryStereochemistryOrganic ChemistryQuinolineSide chainHalidePhysical and Theoretical ChemistryReceptorSelectivityFluorideFluorescence

description

2-Amido-8-urea substituted quinoline derivatives are potent receptors for the binding of halide or benzoate anions in chloroform. The selectivity and affinity of the receptors for fluoride can be tuned by variation of the substituents at the receptor side chains. Computational considerations show that the cleft of the receptors provides space for effective binding of F–, but not bigger anions.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

https://doi.org/10.1002/ejoc.200700130