Iodomethane Oxidation by Dimethyldioxirane: A New Route to Hypoiodous Acid and Iodohydrines

6533b82cfe1ef96bd128f3f5

RESEARCH PRODUCT

Iodomethane Oxidation by Dimethyldioxirane: A New Route to Hypoiodous Acid and Iodohydrines

Cecilia Andreu Carmen Boix-bernardini And Rossella Mello María Elena González Núñez Gregorio Asensio

subject

chemistry.chemical_classification chemistry.chemical_compound chemistry Organic Chemistry Iodide Organic chemistry Physical and Theoretical Chemistry Dimethyldioxirane Photochemistry Biochemistry Hypoiodous acid

description

The oxidation of iodomethane with dimethyldioxirane allows the generation of stable neutral solutions of hypoiodous acid in the absence of any trapping agent for iodide anion. Hypoiodous acid is trapped in situ by addition to representative olefins to give iodohydrines in good yields. The stereochemical study of the products shows the anti-stereospecific nature of the iodohydroxylation reaction.

year	journal	country	edition	language
1999-12-01	Organic Letters

https://doi.org/10.1021/ol9903281

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