6533b82cfe1ef96bd128f6e7

RESEARCH PRODUCT

Multimodal Device for Real-Time Monitoring of Skin Oxygen Saturation and Microcirculation Function

Edgars Kviesis-kipgeUldis RubinsJanis CimursZbignevs MarcinkevicsAndris GrabovskisInga Saknite

subject

AdultMaterials sciencehyperspectral imaginglcsh:BiotechnologyClinical BiochemistryComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONmicrocirculationmultimodal imaging02 engineering and technologyProof of Concept Study01 natural sciencesskin mottlingArticleMicrocirculation010309 opticsSoftwarelcsh:TP248.13-248.650103 physical sciencesHealthy volunteersHumansSegmentationMonitoring PhysiologicSkinHemoglobin SaturationMultimodal imagingHybrid devicebusiness.industryTemperatureHyperspectral imagingGeneral Medicine021001 nanoscience & nanotechnologyOxygenskin oxygen saturation0210 nano-technologybusinessBiomedical engineering

description

The present study introduces a recently developed compact hybrid device for real-time monitoring of skin oxygen saturation and temperature distribution. The prototype involves a snapshot hyperspectral camera, multi-wavelength illuminator, thermal camera, and built-in computer with custom-developed software. To validate this device in-vivo we performed upper arm vascular occlusion on eight healthy volunteers. Palm skin oxygen saturation maps were analyzed in real-time using k-means segmentation algorithm and two-layer optical diffuse model. The prototype system demonstrated a satisfying performance of skin hyperspectral measurements in the spectral range of 507&ndash

10.3390/bios9030097http://dx.doi.org/10.3390/bios9030097