6533b82cfe1ef96bd128f772

RESEARCH PRODUCT

Suprathreshold stochastic resonance behind cancer

Guillermo RodrigoNigel G. Stocks

subject

0301 basic medicineFunctional roleStochastic ProcessesStochastic processComputer scienceCancerStochastic resonance (sensory neurobiology)Biological Sciencesmedicine.diseaseBiochemistry03 medical and health sciencesNoise030104 developmental biology0302 clinical medicinemedicineComputer SimulationMolecular BiologyNeuroscience030217 neurology & neurosurgery

description

Noise in gene expression is pervasive and, in some cases, even fulfills a functional role. Cancer cell populations exploit noise to increase heterogeneity as a defense against therapies. What lies behind this picture is a phenomenon of stochastic resonance led by the collective, rather than by individual cells.

10.1016/j.tibs.2018.04.001http://hdl.handle.net/10261/184427