6533b82cfe1ef96bd128f798

RESEARCH PRODUCT

Recombinant activated factor VII administration in a patient with congenital lack of factor VII undergoing laparoscopic hysterectomy: A case report

Filip A. DąbrowskiNikodem SadlikKrzysztof NowosielskiKrzysztof Nowosielski

subject

Laparoscopic surgerymedicine.medical_specialtymedicine.medical_treatmentHysterectomySurgical bleeding03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCase reportmedicineotorhinolaryngologic diseasesCLIPSLaparoscopycomputer.programming_languageHysterectomyFactor VIImedicine.diagnostic_testbiologybusiness.industrymedicine.diseaseEndometrial hyperplasiaSurgerychemistryRecombinant factor VIIa030220 oncology & carcinogenesisFactor VII deficiencybiology.protein030211 gastroenterology & hepatologySurgeryPremedicationLaparoscopysense organsbusinesscomputercirculatory and respiratory physiology

description

Highlights • Patients with lack of factor VIIa, suffering from abnormal uterine bleedings can be treated with laparoscopic hysterectomy. • Technique using bipolar coagulation and non-absorbable clips is safe and not time consuming. • Pre-operative loading with recombinant factor VIIa must be followed by prolonged supplementation in post-operative period. • We present suggested dosage and length of factor VIIa supplementation based on literature review and own experience.

10.1016/j.ijscr.2020.12.093http://europepmc.org/articles/PMC7804344