6533b82cfe1ef96bd128fcb6

RESEARCH PRODUCT

The main sequelae of preterm birth: Focus on neurodevelopmental disorders

Agata MalteseFrancesco CerroniPalmira RomanoDaniela RussoMargherita SalernoBeatrice GallaiRosa MarottaSerenamarianna LavanoFrancesco LavanoGabriele Tripi

subject

Periventricular leukomalaciaMedicine (all)Preterm birthNeonatal Intensive Care Unit; Periventricular leukomalacia; Preterm birth;Neonatal Intensive Care Unit

description

Preterm birth is a traumatic event that interrupts the physiological processes that allow the development of the Nervous System and the body systems, resulting in a multi-organ dysfunction, of an entity in inverse proportion to the gestational age, which causes respiratory, cardiovascular, metabolic, infectious endocrine problems. and neurological. In particular, at a neurological level, in the most serious cases, for macroscopic lesions of the Central Nervous System, there is the risk of incurring in evolutionary Disabilities (Infantile Cerebral Palsy etc.); but in the absence of severe damage, since the birth occurs at a critical moment of the cerebral development in which the cortex is being organized, it is possible to establish minor deficits, arising from alterations in neural connectivity.

10.19193/0393-6384_2018_5_183http://hdl.handle.net/10447/298076