6533b82cfe1ef96bd128fe7a

RESEARCH PRODUCT

3-(Pyridin-2-yl)[1,2,3]triazolo[1,5-a]quinoline: A Theoretical and Experimental Analysis of Ring-Chain Isomerisation

Ibon AlkortaFrançoise ColobertJosé ElgueroFernando BlancoFrédéric R. LerouxRafael Ballesteros-garridoBelén AbarcaRafael Ballesteros

subject

Steric effectschemistry.chemical_compoundchemistryStereochemistryMetalationOrganic ChemistryQuinolineProton NMRElectronic effectPhysical and Theoretical ChemistryRing (chemistry)Chemical synthesisIsomerization

description

In the course of the synthesis of new fluorophores for molecular recognition an experimental (1H NMR) and theoretical (DFT) study of the ring-chain isomerism of 3-(pyridin-2-yl)[1,2,3]triazolo[1,5-a]quinoline derivatives (A) into 2-([1,2,3]triazolo[1,5-a]pyridin-3-yl)quinoline derivatives (B) has been carried out. The rearrangement is influenced by steric and electronic effects of the substituents present on the quinoline ring. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

yearjournalcountryeditionlanguage
2009-11-01European Journal of Organic Chemistry
https://doi.org/10.1002/ejoc.200900818