6533b82cfe1ef96bd128ffeb

RESEARCH PRODUCT

Design and validation of a neuroprosthesis for the treatment of upper limb tremor.

J. M. Belda-loisS. MenaA. CastilloJuan ÁLvaro GallegoJ.l. PonsEduardo RoconA. D. Koutsou

subject

AdultMaleEngineeringmedicine.medical_specialtyNeuroprostheticsNeural ProsthesesMovementProsthesis DesignUpper ExtremityYoung AdultPhysical medicine and rehabilitationTremormedicineAnimalsHumansPatient treatmentAgedFunctional evaluationbusiness.industryReproducibility of ResultsRoboticsMiddle AgedLarge cohortmedicine.anatomical_structureMedical roboticsPhysical therapyUpper limbFemalebusinessMuscle Contraction

description

Pathological tremor is the most prevalent movement disorder. In spite of the existence of various treatments for it, tremor poses a functional problem to a large proportion of patients. This paper presents the design and implementation of a novel neuroprosthesis for tremor management. The paper starts by reviewing a series of design criteria that were established after analyzing users needs and the expected functionality of the system. Then, it summarizes the design of the neuroprosthesis, which was built to meet the criteria defined previously. Experimental results with a representative group of 12 patients show that the neuroprosthesis provided significant (p <; 0.001) and systematic tremor attenuation (in average 52.33 ± 25.48 %), and encourage its functional evaluation as a potential new treatment for tremor in a large cohort of patients.

10.1109/embc.2013.6610323https://pubmed.ncbi.nlm.nih.gov/24110510