6533b82cfe1ef96bd1290144

RESEARCH PRODUCT

Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(II) ions

Aida NebotBram VerbelenMarlon ValckenborghWim DehaenMario InclánEnrique García-españa

subject

Tris010405 organic chemistryLigandGeneral Chemical EngineeringInorganic chemistrychemistry.chemical_elementGeneral Chemistry010402 general chemistry01 natural sciencesCopperCombinatorial chemistryFluorescence0104 chemical scienceschemistry.chemical_compoundchemistryBODIPYpolyaminechemosensorsSurface modificationAmine gas treatingBODIPYBoroncopper(II)

description

Two simple fluorescent sensors for Cu(II) ions were synthesized in two reaction steps, using recently developed C–H functionalization reactions for boron dipyrrins, starting from a standard 8-aryl-BODIPY dye and a tris(2-aminoethyl)amine (TREN) ligand. At pH 5, the resulting BODIPY–TREN conjugates are demonstrated to be promising, highly selective, water soluble, Cu(II) sensors that can permeate the cell membrane. crosscheck: This document is CrossCheck deposited related_data: Supplementary Information identifier: Bram Verbelen (ORCID) identifier: Wim Dehaen (ORCID) copyright_licence: The Royal Society of Chemistry has an exclusive publication licence for this journal copyright_licence: This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0) history: Received 24 November 2016; Accepted 20 December 2016; Version of Record published 13 January 2017 ispartof: RSC Advances vol:7 issue:6 pages:3066-3071 status: published

10.1039/c6ra27299ahttps://lirias.kuleuven.be/handle/123456789/570298