0000000000599532

AUTHOR

Aida Nebot

showing 4 related works from this author

Mn(II) complexes of scorpiand-like ligands. A model for the MnSOD active centre with high in vitro and in vivo activity

2015

Manganese complexes of polyamines consisting of an aza-pyridinophane macrocyclic core functionalised with side chains containing quinoline or pyridine units have been characterised by a variety of solution techniques and single crystal x-ray diffraction. Some of these compounds have proved to display interesting antioxidant capabilities in vitro and in vivo in prokaryotic (bacteria) and eukaryotic (yeast and fish embryo) organisms. In particular, the Mn complex of the ligand containing a 4-quinoline group in its side arm which, as it happens in the MnSOD enzymes, has a water molecule coordinated to the metal ion that shows the lowest toxicity and highest functional efficiency both in vitro …

Fish ProteinsSaccharomyces cerevisiae ProteinsStereochemistryOryziasSaccharomyces cerevisiaeLigandsFish embryo modelsBiochemistryAntioxidantsInorganic Chemistrychemistry.chemical_compoundAntioxidant activityIn vivoCatalytic DomainPyridineSide chainEscherichia coliAnimalschemistry.chemical_classificationManganeseBacteriaLigandSuperoxide DismutaseEscherichia coli ProteinsQuinolineYeastIn vitroYeastMn(II) complexesEnzymechemistryModels ChemicalPolyazamacrocyclic scorpiandsQuinolines
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Efficient two-step synthesis of water soluble BODIPY–TREN chemosensors for copper(II) ions

2017

Two simple fluorescent sensors for Cu(II) ions were synthesized in two reaction steps, using recently developed C–H functionalization reactions for boron dipyrrins, starting from a standard 8-aryl-BODIPY dye and a tris(2-aminoethyl)amine (TREN) ligand. At pH 5, the resulting BODIPY–TREN conjugates are demonstrated to be promising, highly selective, water soluble, Cu(II) sensors that can permeate the cell membrane. crosscheck: This document is CrossCheck deposited related_data: Supplementary Information identifier: Bram Verbelen (ORCID) identifier: Wim Dehaen (ORCID) copyright_licence: The Royal Society of Chemistry has an exclusive publication licence for this journal copyright_licence: Thi…

Tris010405 organic chemistryLigandGeneral Chemical EngineeringInorganic chemistrychemistry.chemical_elementGeneral Chemistry010402 general chemistry01 natural sciencesCopperCombinatorial chemistryFluorescence0104 chemical scienceschemistry.chemical_compoundchemistryBODIPYpolyaminechemosensorsSurface modificationAmine gas treatingBODIPYBoroncopper(II)
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CCDC 1020483: Experimental Crystal Structure Determination

2015

Related Article: M. Paz Claresa, Carolina Serena, Salvador Blasco, Aida Nebot, Lucas del Castillo, Conxa Soriano, Antonio Domènech, Ana Virginia Sánchez-Sánchez, Laura Soler-Calero, José Luis Mullor, Antonio García-España, Enrique García-España|2015|J.Inorg.Biochem.|143|1|doi:10.1016/j.jinorgbio.2014.11.001

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(N-(2-(36915-Tetra-azabicyclo[9.3.1]pentadeca-1(15)1113-trien-6-yl)ethyl)propane-13-diamine)-manganese(ii) diperchlorateExperimental 3D Coordinates
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CCDC 999624: Experimental Crystal Structure Determination

2015

Related Article: M. Paz Claresa, Carolina Serena, Salvador Blasco, Aida Nebot, Lucas del Castillo, Conxa Soriano, Antonio Domènech, Ana Virginia Sánchez-Sánchez, Laura Soler-Calero, José Luis Mullor, Antonio García-España, Enrique García-España|2015|J.Inorg.Biochem.|143|1|doi:10.1016/j.jinorgbio.2014.11.001

Space GroupCrystallographyCrystal System(N-((Pyridin-2-yl)methyl)-2-(36915-tetra-azabicyclo[9.3.1]pentadeca-1(15)1113-trien-6-yl)ethanamine)-manganese(ii) diperchlorateCrystal StructureCell ParametersExperimental 3D Coordinates
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