6533b82cfe1ef96bd12901ef

RESEARCH PRODUCT

Effects of the prolonged thoracic epidural analgesia on ventilation function and complication rate after the lung cancer surgery.

Māris MihelsonsNataļja JakušenkoSanita UdreImmanuels TaivansUldis KopeikaGunta Strazda

subject

Plaučiai--Komp¬likacijosVital capacitymedicine.medical_specialtyLung NeoplasmsTime Factorsmedicine.medical_treatmentVital CapacityAnesthesia GeneralLungs--SurgeryPneumonectomyPostoperative Complicationsthoracic epidural analgesiaCarcinoma Non-Small-Cell LungForced Expiratory VolumemedicineHumansProspective StudiesProspective cohort studyPneumonectomyLungs--ComplicationsPain MeasurementLung cancer surgeryPain Postoperativebusiness.industryMortality rateIncidencePostoperative complicationlung functionGeneral MedicineSurgerylung surgery; thoracic epidural analgesia; lung function; postoperative complicationsAnalgesia Epidurallung surgeryAnesthesiaData Interpretation StatisticalAnestheticBreathingPlaučiai--ChirurgijabusinessPulmonary Ventilationmedicine.drug

description

Thoracic epidural analgesia has been considered to have a good anesthetic efficacy and to decrease the postoperative complication rate, while its effect upon the ventilation function is still the topic of many clinical studies. The aim of this study was to evaluate the course of early postoperative period using thoracic epidural analgesia. Material and methods. A total of 453 patients undergoing the operation due to the non–small cell carcinoma were selected and examined. Their postoperative complications and mortality rate were evaluated. In 79 patients, arterial oxygen saturation (SaO2), forced vital capacity, forced expiratory volume in the first second, and the efficacy of analgesia were analyzed within the first 7 days after the operation. These patients were divided into subgroups according to the type of the operation – lobectomy or pneumonectomy – and the type of analgesia – thoracic epidural analgesia or opiates administered intramuscularly (control group). Results. A better statistically significant efficacy of analgesia was observed in thoracic epidural analgesia group than in the control group (visual analog pain scale score 2.5 versus 5.3, P&lt

https://pubmed.ncbi.nlm.nih.gov/17413248