6533b82dfe1ef96bd12908b0

RESEARCH PRODUCT

Donellanic acids A–C: new cyclopropanic oleanane derivatives from Donella ubanguiensis (Sapotaceae)

Victor KueteSamuel O. YeboahVincent RinchevalAbegaz M. BerhanuPascal WafoDieter SchollmeyerTill OpatzAurelie Vigee Barry Songfack DjoumessiLouis P. SandjoLouis P. SandjoBonaventure T. NgadjuiJohannes C. Liermann

subject

biologyStereochemistryOrganic Chemistrybiology.organism_classificationAntimicrobialBiochemistrySapotaceaeNmr dataMass spectrometricchemistry.chemical_compoundTriterpenoidchemistryDrug DiscoveryOrganic chemistryOleanane

description

Abstract Three new cyclopropanic oleanane triterpenoids and ten known compounds were obtained from Donella ubanguiensis using chromatographic methods. The structures were established on the basis of mass spectrometric and NMR data and by comparison with values reported in the literature. The structures of the new compounds were confirmed by X-ray crystallography. A part of the isolated compounds was evaluated for cytotoxic and antimicrobial activities.

https://doi.org/10.1016/j.tet.2012.04.027