6533b82dfe1ef96bd1291362

RESEARCH PRODUCT

Cardiovascular risk and events in polycystic ovary syndrome

Enrico Carmina

subject

medicine.medical_specialtyPCOS Cardiovascular risk myocardial infarction stroke atherosclerosisSettore MED/09 - Medicina InternaDiseaseAndrogen ExcessSeverity of Illness IndexSettore MED/13 - EndocrinologiaInsulin resistanceRisk FactorsInternal medicinePrevalencemedicineHumansEndothelial dysfunctionAbdominal obesityEvidence-Based Medicinebusiness.industryHyperandrogenismObstetrics and GynecologyGeneral Medicinemedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareSettore MED/40 - Ginecologia E OstetriciaPolycystic ovaryPostmenopauseEndocrinologyPremenopauseCardiovascular DiseasesFemalemedicine.symptombusinessDyslipidemiaPolycystic Ovary Syndrome

description

Young women with polycystic ovary syndrome (PCOS) present a high risk for cardiovascular disease because of the presence of abdominal obesity, insulin resistance and androgen excess. In addition, they present with endothelial dysfunction and early signs of atherosclerosis (increased carotid intima-media thickness and increased coronary calcium). However, the evidence of increased cardiovascular events during the postmenopausal age is relatively small, although some recent studies have indicated a slight increase in the severity of cardiovascular disease in women who had PCOS during their fertile age. The discrepancy between cardiovascular risk in young age and postmenopausal cardiovascular events may depend on changes in the risk that happen during the late fertile age or on overestimation of early atherosclerotic signs.

yearjournalcountryeditionlanguage
2009-10-09Climacteric
https://doi.org/10.1080/13697130903003842