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RESEARCH PRODUCT

Non-coding RNAs and Coronary Artery Disease

Fabian Sanchis-gomarHelios Pareja-galeanoGiuseppe LippiSalvador Mena-molláFernando De La Guía-galipiensoAlejandro Cardona-monzonísJosé Luis García-giménezFederico V. Pallardó

subject

Enfermedad cardiovascularRNABiomarkerDiseaseComputational biologyGenética humanaBiologyNon-coding RNAPrecision medicinemedicine.diseaseARNCoronary artery disease (CAD)Coronary artery disease03 medical and health scienceslncRNA0302 clinical medicineBiomarker; Coronary artery disease (CAD); circRNA; lncRNA; miRNAGene expressionmicroRNAmedicineBiomarker (medicine)Cardiopatía coronariacircRNA030212 general & internal medicinemiRNA

description

Coronary artery disease (CAD) is the leading death cause worldwide. Non-coding RNA (ncRNA) are key regulators of genetic expression and thus can affect directly or indirectly the development and progression of different diseases. ncRNA can be classified in several types depending on the length or structure, as long non-coding RNA (lncRNA), microRNA (miRNA) and circularRNA (circRNA), among others. These types of RNA are present within cells or in circulation, and for this reason they have been used as biomarkers of different diseases, therefore revolutionizing precision medicine. Recent research studied the capability of circulating ncRNA to inform about CAD presence and predict the outcome of the disease. In this chapter we present a list of the miRNA, lncRNA and circRNA which are potential biomarkers of CAD. Sin financiación 2.126 JCR (2018) Q2, 30/87 Biology; Q3, 86/136 Medicine, Research & Experimental UEM

yearjournalcountryeditionlanguage
2020-01-01
https://doi.org/10.1007/978-981-15-1671-9_16