6533b82dfe1ef96bd1291452

RESEARCH PRODUCT

Capillary electrophoretic and extraction conditions for the analysis of Catha edulis FORKS active principles

Sonia SuardiVeniero GambaroSebastiano ArnoldiGabriella RodaVincenzo LibertiArgo AChiara Rusconi

subject

AnalyteChromatographyMolecular StructureCathinonePlant ExtractsChemistryCapillary actionPhenylpropanolamineExtraction (chemistry)Vegetable materialElectrophoresis CapillaryReproducibility of ResultsCathaRepeatabilityPathology and Forensic MedicineElectrophoresisAlkaloidsSettore MED/43 - Medicina LegaleCathinone Cathine PhenylpropanolaminemedicineLawCathinemedicine.drug

description

A capillary electrophoretic method, which allowed the detection and separation of the active principles of Catha edulis, i.e. cathinone, cathine and phenylpropanolamine, was developed. A suitable internal standard (nicotinamide), which permitted the quantification of the analytes reducing the variability of the migration times due to EOF changes, was identified. The analytical method was validated, assessing linearity, sensitivity and repeatability, showing optimal features for the analysis of the vegetable material. Moreover extraction conditions were investigated to achieve the exhaustion of the plant material in the fastest and most efficient way to meet the requirements of the Court.

yearjournalcountryeditionlanguage
2013-05-01
http://hdl.handle.net/10447/75859