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RESEARCH PRODUCT
Study of Morphology of Reactive Dissolution Interface Using Fractal Geometry
Jean-claude GnanouC. AndrèsBernard ChaillotAnne TromelinY. Pourcelotsubject
Materials scienceMorphology (linguistics)Pharmaceutical ScienceThermodynamics02 engineering and technology030226 pharmacology & pharmacyFractal dimension03 medical and health sciences0302 clinical medicineFractalfractaldimension[CHIM.ANAL]Chemical Sciences/Analytical chemistrysurface morphologysurfaceParticle SizeSolubilitydissolution rateDissolutionMicroporous material021001 nanoscience & nanotechnology[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry[SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacologySolubilityMicroscopy Electron ScanningParticle size0210 nano-technologySpecific populationdescription
J. Pharm. Sci. ISI Document Delivery No.: VF662 Times Cited: 7 Cited Reference Count: 15 Tromelin, A Gnanou, JC Andres, C Pourcelot, Y Chaillot, B; International audience; The determination of reactive fractal dimension was carried out using two forms of the Noyes-Whitney equation, -dQ/dt = K(Q/Q(0))(DR/3) and -d Q/dt = K' R(DR-3) using the Richardson plot on the basis of previous data obtained by dissolution of an orthoboric acid powder. The correlation of the results provided by the two ways of calculation allows proposal of the hypothesis that dissolution begins on a specific population of reactive sites and probably promotes the formation of microporous volumes or cracks.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1996-09-01 | Journal of Pharmaceutical Sciences |