6533b82efe1ef96bd129271b

RESEARCH PRODUCT

In Vitro Techniques

C. Yan ChengJacques PaiementBarbara KorbeiRichard J. ChiBarbara GajkowskaJohn F. HessTakahiro SasakiSven T. LiffersEric BertrandFélix M. GoñiIvan WalevElizabeth SztulChunhong YangReiner PetersDolores D. MrukH. Dariush FahimiWilliam J. BrownRobin YoungJean M. UnderwoodIgor BronsteinMatthias RögnerK. ChambersStefan WagnerArnold H. GreenbergMartin W. HetzerMarina KriajevskaBen De KruijffDoris KirschnerIan G. MillsAna V. VillarDavid F. HolmesKoert N.j. BurgerHarald PaulsenMatthew K. HigginsJun TanKarl E. KadlerDaniela S. DimitrovaThomas C. S. KellerStephanie BoggaschJulie BenesovaA. DoodyAnton I.p.m. De KroonLuis Eduardo Soares NettoJudie B. AlimontiRobert GniadeckiJeffrey A. NickersonShin-ichi HisanagaYa Sheng GaoJinnan XiaoSusan BaneJohn C. VossTerrence TownEugene LukanidinBrian J. PeterJ. Robin HarrisGeneviève AlmouzniYuechueng LiuRutger W.h.m. StaffhorstAlicia AlonsoKenji UédaHelmut KirchhoffNathaniel G.n. MiltonMeinolf ThiemannTobias C. WaltherAnuradha PradhanF.-xabier ContrerasRoland FoisnerWinfried HaasePaul G. Fitzgerald

subject

GeneticsIn Vitro TechniquesFda approvalGenomicsContext (language use)Full colorBiologyDrug formulationsData scienceStructure and function

description

Driven in part by the development of genomics, proteomics, and bioinformatics as new disciplines, there has been a tremendous resurgence of interest in physical methods to investigate macromolecular structure and function in the context of living cells. This volume in Methods in Cell Biology is devoted to biophysical techniques in vitro and their applications to cellular biology. The volume covers methods-oriented chapters on fundamental as well as cutting-edge techniques in molecular and cellular biophysics.This book is directed toward the broad audience of cell biologists, biophysicists, pharmacologists, and molecular biologists who employ classical and modern biophysical technologies or wish to expand their expertise to include such approaches. It will also interest the biomedical and biotechnology communities for biophysical characterization of drug formulations prior to FDA approval. It describes techniques in the context of important biological problems. It delineates critical steps and potential pitfalls for each method. It includes full color plates to illustrate techniques.

https://doi.org/10.1002/0470033487.ch6