6533b82efe1ef96bd12928ac
RESEARCH PRODUCT
Reliability of manual segmentation of cornea, contact lens and tear film using a high-resolution OCT
Patrícia RodriguesAlejandro CerviñoJosé Manuel González-méijomeDaniela Lopes-ferreiraAntónio QueirósAndreia Catarinosubject
Materials scienceManual layer segmentationOpticsCLs upper limitsOptical coherence tomographyCorneamedicineEpithelial thicknessRepeatabilityScience & Technologymedicine.diagnostic_testOptical coherence tomographybusiness.industryResolution (electron density)RepeatabilityAtomic and Molecular Physics and Opticseye diseasesTear film thicknessContact lensCorneal thicknessmedicine.anatomical_structureManual segmentationsense organsbusinessBiomedical engineeringdescription
In this study, we aimed to evaluate the intra/inter-session and intra/inter-observer variability of manual segmentation of thickness of the pre-lens tear film, contact lens (CL), post-lens tear film, epithelium, bowman’s layer, stroma and the whole cornea and CLs with a flat and a steep fit, using a commercial high-resolution spectral domain optical coherence tomographer (OCT). Two different observers obtained three repeated measures in two separate sessions. A high correlation was found between the values obtained by the two different observers, except for the thinner layers, epithelium, and Bowman’s layer. Inter-observer analysis showed a high consistency in the measurements obtained by both observers (r 2 ≥ 0.80; p 0.05). The present results suggest that manual segmentation of anterior segment OCT images in CL wearers provides acceptable levels of repeatability between observers and between different sessions for the thinner layers, while presenting a high level of repeatability for the thicker layers.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-09 |