6533b82efe1ef96bd12928f3
RESEARCH PRODUCT
Cops and robbers: putative evolution of copper oxygen-binding proteins.
Heinz DeckerNora B. Terwilligersubject
PhysiologyCopper proteinCopper metabolismchemistry.chemical_elementAquatic ScienceEvolution MolecularPrimary immune responseAnimalsBinding siteMolecular BiologyEcology Evolution Behavior and SystematicsBinding SitesbiologyMonophenol MonooxygenaseOxygen transportActive siteCopperOxygenchemistryBiochemistryInsect ScienceHemocyaninsbiology.proteinAnimal Science and ZoologyOxygen bindingCopperdescription
Two closely related copper proteins, phenoloxidase and haemocyanin, are known to be involved in different physiological functions such as the primary immune response and oxygen transport. Although the proteins differ structurally, they have the same active site by which dioxygen is bound. Recent results reveal that haemocyanin also exhibits phenoloxidase activity. A scenario is proposed for the evolutionary relationships among copper oxygen-binding proteins (COPs).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-06-15 | The Journal of experimental biology |