6533b82efe1ef96bd12930e4

RESEARCH PRODUCT

Antioxidants and carcinogen metabolism

Regine Kahl

subject

PharmacologyAntioxidantfood.ingredientMechanism (biology)Chemistrymedicine.medical_treatmentFood additiveCarcinogen MetabolismToxicologyBroad spectrumfoodBiochemistryChemical carcinogensmedicine

description

Abstract Supplementation of diet with synthetic antioxidants has been shown to protect animals against a broad spectrum of chemical carcinogens. Some interest has been expressed in the use of these food additives as possible prophylactic agents. However, such considerations appear premature in view of the fact that the protective mechanism has not yet been elucidated. The present communication reviews the effect of antioxidants on carcinogen-metabolizing enzymes, one of the major candidates in the interpretation of the protective antioxidant action.

yearjournalcountryeditionlanguage
1982-01-01Trends in Pharmacological Sciences
https://doi.org/10.1016/0165-6147(82)91015-x