Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery

6533b82efe1ef96bd12931c6

RESEARCH PRODUCT

Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery

Daniele Polisano Dario Buioni Paolo Nardi Maria Sabrina Ferrante Calogera Pisano Carmela Rita Balistreri Giovanni Ruvolo Daniele Trombetti Laura Asta Calogero Foti Fabio Bertoldo Claudia Altieri

subject

Aging Food intake medicine.medical_specialty Cachexia MEDLINE lcsh:TX341-641 Review frailty malnutrition 030204 cardiovascular system & hematology age related syndrome Cachexia sarcopenia Settore MED/34 Eating 03 medical and health sciences 0302 clinical medicine Preoperative Care medicine Humans Age related syndrome Frailty Malnutrition Sarcopenia Settore MED/05 - Patologia Clinica 030212 general & internal medicine Cardiac Surgical Procedures Intensive care medicine Nutrition and Dietetics business.industry Stressor Preoperative Exercise Resistance Training medicine.disease Cardiac surgery Malnutrition Phenotype vascular aging Cardiovascular Diseases Sarcopenia Blood Vessels Vascular aging Sedentary Behavior business lcsh:Nutrition. Foods and food supply Biomarkers Food Science

description

Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation.

year	journal	country	edition	language
2021-02-01	Nutrients

https://doi.org/10.3390/nu13020517

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