Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68

6533b82efe1ef96bd12932f5

RESEARCH PRODUCT

Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68

Carsten Burchardt Frank Roesch Bradley P. Waldron David Parker Dmitry S. Yufit Melanie Zimny

subject

Chemistry Metals and Alloys chemistry.chemical_element General Chemistry Pet imaging Tricarboxylate Combinatorial chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Labelling Materials Chemistry Ceramics and Composites Organic chemistry Gallium

description

Pre-organised tricarboxylate ligands based on 6-amino-perhydro-1,4-diazepine bind (68)Ga rapidly and selectively in acetate buffer at pH 4 to 7, forming kinetically stable complexes suitable for use in PET imaging.

year	journal	country	edition	language
2012-12-06	Chem. Commun.

https://doi.org/10.1039/c2cc37544c

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