6533b82efe1ef96bd1293334
RESEARCH PRODUCT
Synthesis of Polyfused Heterocycle Derivatives Containing the Dipyridoimidazole Core by Friedländer’s Reaction: Access to Analogs of Ellipticine
Nicolas DesboisFlorence FauvelleJean-claude TeuladeJean-michel ChezalClaire LartigueYves BlacheEmmanuel MoreauAlain GueiffierOlivier ChavignonJean-claude MadelmontJean-claude Debouzysubject
StereochemistryIntercalation (chemistry)[CHIM.THER]Chemical Sciences/Medicinal ChemistryFluorene010402 general chemistry01 natural sciencesAnalytical ChemistryEllipticinechemistry.chemical_compound[ CHIM.ORGA ] Chemical Sciences/Organic chemistryPyridine[CHIM.COOR]Chemical Sciences/Coordination chemistryComputingMilieux_MISCELLANEOUSPharmacologybiology[CHIM.ORGA]Chemical Sciences/Organic chemistry010405 organic chemistryOrganic Chemistry[ CHIM.COOR ] Chemical Sciences/Coordination chemistry[ CHIM.THER ] Chemical Sciences/Medicinal ChemistryPhenanthrenebiology.organism_classification0104 chemical scienceschemistryTetra[ CHIM.RADIO ] Chemical Sciences/Radiochemistry[CHIM.RADIO]Chemical Sciences/Radiochemistrydescription
Reaction of 3-amino-2-formylimidazo[l,2-a]pyridine with various aldehydes and ketones by Friedlander's methodology afforded an entry to dipyridoimidazole, tri(tetra)azacyclopenta[b]fluorene, tri(tetra)azabenzo[b]-fluorene and triazaindeno[2,1-b]phenanthrene derivatives. Intercalation with a synthetic oligodeoxynucleotide was examined.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-01-01 | HETEROCYCLES |