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RESEARCH PRODUCT
The Hippo Show Must Go On: YAP Activation as a Therapeutic Strategy in Colorectal Cancer
Giorgio StassiVeronica Veschisubject
0303 health sciencesHippo signaling pathwayColorectal cancerCellWnt signaling pathwayCell BiologyBiologymedicine.diseasedigestive system diseaseslaw.invention03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurelawGeneticsmedicineCancer researchMolecular MedicineSuppressorYAP colorectal cancer Hippo pathway Wnt pathwayStem cellTranscription factor030217 neurology & neurosurgeryFunction (biology)030304 developmental biologydescription
The role of Hippo pathway in colorectal cancer (CRC) initiation and progression has been controversial. In this issue of Cell Stem Cell, Cheung et al. (2020) shed new light on a distinct function of the transcriptional co-activator YAP as a tumor suppressor and Wnt pathway inhibitor in CRC.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-10-01 | Cell Stem Cell |