6533b82efe1ef96bd1293ca4
RESEARCH PRODUCT
Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs
Luciano RausaRizzo FpNicolo' GebbiaF. BiondoMichele Pavone-macalusoCaramia Gsubject
Oncologymedicine.medical_specialtyPathologyAdministration TopicalUrologyTransplantation HeterologousHuman bladderDrug ResistanceHamsterAntineoplastic AgentsBLADDER PAPILLOMAThiophenesFluorescenceCricetinaeInternal medicinemedicineAnimalsHumansGlycosidesMelphalanIn vivo cytotoxicityPodophyllotoxinCell NucleusCarcinoma Transitional Cellbusiness.industryDaunorubicinDemecolcineDNA NeoplasmCytotoxicity Tests ImmunologicMicroscopy FluorescenceUrinary Bladder NeoplasmsDoxorubicinProtein BiosynthesisAntineoplastic DrugsOxidoreductasesbusinessNeoplasm TransplantationThiotepadescription
A number of laboratory tests can be employed to examine the sensitivity of human bladder tumour cells to various chemotherapeutic agents.-Their principles and methods, and some preliminary results, are described with special reference to certain in vitro and in vivo cytotoxicity tests and to heterotransplantation in the hamster. Satisfactory agreement has sometimes been observed between experimental results and clinical responses, but our experience is still very limited.-The employment of several such tests would probably lead to a greater degree of reliability in the laboratory assessment of the sensitivity of bladder tumours to cytotoxic drugs.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1973-05-01 | Urological Research |