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RESEARCH PRODUCT
Can aminothiols be distinguished from reactive oxygen species?
Catherine Vergely Luc Rochettesubject
0301 basic medicinemedicine.medical_specialtyAntioxidantmedicine.medical_treatmentCystine030204 cardiovascular system & hematologymedicine.disease_causeCoronary artery disease03 medical and health scienceschemistry.chemical_compound0302 clinical medicine[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicinemedicineIn patientComputingMilieux_MISCELLANEOUSchemistry.chemical_classificationReactive oxygen speciesbusiness.industryPlasma levelsGlutathionemedicine.disease3. Good health030104 developmental biologyEndocrinologychemistryCardiologyCardiology and Cardiovascular MedicinebusinessOxidative stressdescription
Glutathione is considered the major natural antioxidant, protecting cells from oxidative stress. Patel and colleagues used plasma levels of the aminothiols cystine and glutathione to quantify oxidative stress in patients with coronary artery disease, and show that the cystine/glutathione ratio is associated with increased mortality. Is this a new approach for clinical risk stratification?
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-03-01 |