6533b82efe1ef96bd1293e59

RESEARCH PRODUCT

Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment

Silje AndreassenAnne Marit SolheimUnn LjøstadÅSe MyglandÅSlaug Rudjord LorentzenHarald ReisoMona Kristiansen BeyerHanne Flinstad HarboGro Christine Christensen LøhaugenRandi Eikeland

subject

Behavioral NeuroscienceCognitionVDP::Medisinske Fag: 700::Helsefag: 800HumansLyme NeuroborreliosisProspective StudiesNervous System DiseasesFatigue

description

Background Long-term cognitive problems after neuroborreliosis treatment remain a subject of debate. We have previously shown that cognitive problems are not present in the acute phase of neuroborreliosis, although fatigue is common. The aim of this study was to re-assess the same patient cohort and evaluate long-term outcomes. Methods In this follow-up, we re-assessed 58 patients with well-characterized neuroborreliosis 12 months after completing treatment. The same protocol with eight subtests measuring attention and processing speed and the Fatigue Severity Scale (FSS) were used to compare the results from the acute phase to 12 months post treatment. Results We found no changes in attention or processing speed but a reduction in the level of fatigue (median score on FSS: 4.9 vs. 3.9, p < .001) from the acute phase to 12 months post treatment. Conclusion The patient group did not develop problems with attention or processing speed post treatment, while the level of fatigue decreased. publishedVersion

yearjournalcountryeditionlanguage
2022-01-01
https://hdl.handle.net/11250/3010287