6533b82efe1ef96bd1293e7d

RESEARCH PRODUCT

From transformation to chronification of migraine : pathophysiological and clinical aspects

M. Torres-ferrúsF. UrsittiA. Alpuente-ruizF. BrunelloD. ChiappinoT. De VriesS. Di MarcoS. FerlisiL. GuerritoreN. Gonzalez-garciaA. Gonzalez-martinezD. KhutorovM. KritsilisA. KyrouT. MakeevaA. Minguez-olaondoL. PilatiA. SerrienO. TsurkalenkoD. Van Den AbbeeleW. S. Van HoogstratenC. LamplUniversitat Autònoma De BarcelonaVhir Vall D'hebron Institut De Recerca

subject

medicine.medical_specialtyNeurologyMigraine Disorderslcsh:MedicineNeurophysiologyNeuroimagingNeuroimagingNeurological disorderReview ArticleBioinformaticsPathophysiologyEpigenesis GeneticTransformationChronic MigraineNeuroimagingEpidemiologyGeneticsMedicineHumansPathologicalChronic migrainebusiness.industrylcsh:RGeneral MedicineBiomarkermedicine.diseaseBiomarker (cell)Animal modelsAnesthesiology and Pain MedicineMigraineRisk factorsChronic DiseaseDisease ProgressionNeurology (clinical)business

description

AbstractChronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. Ample studies have attempted to identify factors associated with migraine transformation from different perspectives. Understanding CM as a pathological brain state with trigeminovascular participation where biological changes occur, we have completed a comprehensive review on the clinical, epidemiological, genetic, molecular, structural, functional, physiological and preclinical evidence available.

https://ddd.uab.cat/record/227742