6533b82efe1ef96bd1293efa
RESEARCH PRODUCT
Biotransformation and toxicity effect of monoanthraquinone dyes during Bjerkandera adusta CCBAS 930 cultures.
Jan GmińskiKonrad A. SzychowskiTeresa Korniłłowicz-kowalskaKamila Rybczyńska-tkaczyksubject
Health Toxicology and Mutagenesis0211 other engineering and technologiesAnthraquinones02 engineering and technology010501 environmental sciences01 natural sciencesAnthraquinoneLepidium sativumchemistry.chemical_compoundBjerkandera adustaBiotransformationPhenolsHumansColoring AgentsBiotransformation0105 earth and related environmental sciences021110 strategic defence & security studiesbiologyChemistryPublic Health Environmental and Occupational HealthBiosorptionGeneral MedicineBiodegradationbiology.organism_classificationPollutionAliivibrio fischeriBiodegradation EnvironmentalBiochemistryToxicityPhytotoxicityEcotoxicityCoriolaceaedescription
Abstract The aim of this study was to evaluate of possibility of biotransformation and toxicity effect of monoanthraquinone dyes in cultures of Bjerkandera adusta CCBAS 930. Phenolic compounds, free radicals, phytotoxicity (Lepidium sativum L.), ecotoxicity (Vibrio fischeri) and cytotoxicity effect were evaluated to determine the toxicity of anthraquinone dyes before and after the treatment with B. adusta CCBAS 930. More than 80% of ABBB and AB129 was removed by biodegradation (decolorization) and biosorption, but biodegradation using oxidoreductases was the main dye removing mechanism. Secondary products toxic to plants and bacteria were formed in B. adusta strain CCBAS 930 cultures, despite efficient decolorization. ABBB and AB129 metabolites increased reactive oxygen species (ROS) production in human fibroblasts, but did not increase LDH release, did not affect the resazurine reduction assay and did not change caspase-9 or caspase-3 activity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-03-01 | Ecotoxicology and environmental safety |