6533b82efe1ef96bd1294478
RESEARCH PRODUCT
Regio- and stereoselective oxyfunctionalization at C-1 and C-5 in sesquiterpene guaianolides
Begoña GarcíaGonzalo BlayVictoria BarguesJ. R. PedroLuz Cardonasubject
Hydroxylationchemistry.chemical_compoundAllylic rearrangementchemistryStereochemistryOrganic ChemistryDrug DiscoveryOrganic chemistryStereoselectivitySesquiterpeneBiochemistrydescription
Abstract The regio- and stereoselective functionalization at C-1 and C-5 positions in a guaiane skeleton by allylic hydroxylation are described. The stereochemistry of the resulting compounds are identical to those of the majority of natural 1- and 5-hydroxy-guaianolides.
year | journal | country | edition | language |
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1998-02-01 | Tetrahedron |