6533b82ffe1ef96bd1294ea9
RESEARCH PRODUCT
Immune pathogenesis of hepatitis A
A. VallbrachtB. Fleischersubject
business.industryMechanism (biology)virusesfungivirus diseasesHepatitis AAutologous lymphocytebiochemical phenomena metabolism and nutritionmedicine.diseaseVirologydigestive system diseasesHepatitis a virusImmune pathogenesismedicineLiver damageHepatocellular injurybusinessdescription
In an effort to elucidate the mechanism of liver damage resulting from Hepatitis A virus (HAV) infection, we have studied infected skin fibroblasts and autologous lymphocytes from HAV patients. We report here that HLA-restricted virus-specific T cells play an essential role in HAV-related hepatocellular injury.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-01-01 |