6533b82ffe1ef96bd1294fd9

RESEARCH PRODUCT

Guest-Induced Selective Functionalization of Polyaza[n]paracyclophanes

subject

description

A new strategy to the preparation of selectively functionalized polyazamacrocycles is presented. Polyaza[n]paracyclophane receptors are able to efficiently direct their own selective functionalization upon interaction with simple guests such as metal cations. This enables the preparation of novel receptors functionalized at one of the benzylic nitrogen atoms with a variety of groups. Selective difunctionalization at both benzylic positions can also be achieved in this way.