6533b82ffe1ef96bd12959c0

RESEARCH PRODUCT

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subject

0301 basic medicineRecurrent infectionsbiologybusiness.industryChronic lymphocytic leukemiaImmune defectHematologymedicine.disease03 medical and health scienceschemistry.chemical_compound030104 developmental biologychemistryimmune system diseaseshemic and lymphatic diseasesIbrutinibFrequent infectionsMyeloid cellsImmunologybiology.proteinMedicineBruton's tyrosine kinasebusinessReceptor

description

Recurrent infections are common complications in patients with non-Hodgkin lymphomas, for example, chronic lymphocytic leukemia (CLL). The secondary immune defect as the underlying cause of frequent infections is in part due to hypoimmunoglobulinemia or diminished T- and B-cell responses suppressing