6533b82ffe1ef96bd1295b04

RESEARCH PRODUCT

A heterochromatic P sequence in the D. subobscura genome.

M. J. Martínez-sebastiánNuria ParicioR. De Frutos

subject

DNA ComplementaryX ChromosomeEuchromatinTranscription GeneticHeterochromatinMolecular Sequence DataPlant ScienceBiologyGenomeP elementHeterochromatinGeneticsAnimalsCloning MolecularX chromosomePhylogenySequence (medicine)GeneticsPhylogenetic treeBase SequenceChromosomeChromosome MappingGeneral MedicineSequence Analysis DNAInsect ScienceDNA Transposable ElementsAnimal Science and ZoologyDrosophilaSequence Alignment

description

The study of a heterochromatic P sequence of D. subobscura reveals that it is a degraded element, located at the centromeric region of the A chromosome (X chromosome in this species), and that it is strongly diverged from the euchromatic P sequences previously described in this species. This heterochromatic sequence is composed of some P element fragments embedded in undefined beta-heterochromatic sequences. These mosaic P sequences do not show any transcriptional activity and seem to be ancient parasites of the D. subobscura genome. Phylogenetic analyses indicate that both the euchromatic and heterochromatic P sequences of D. subobscura could come from an ancestral element which was present before the divergence of the subobscura species cluster.

10.1007/bf00132536https://pubmed.ncbi.nlm.nih.gov/7958941