6533b82ffe1ef96bd1295b2c
RESEARCH PRODUCT
Biomaterials and bioactive molecules to drive differentiation in striated muscle tissue engineering
Dario ColettiDario ColettiValentina Di FeliceGiancarlo Fortesubject
Muscle tissueStriated muscle tissuePathologymedicine.medical_specialtyPhysiology030204 cardiovascular system & hematologyRegenerative MedicineRegenerative medicinelcsh:PhysiologyBiomaterials03 medical and health sciencescardiac tissue engineering0302 clinical medicineTissue engineeringPhysiology (medical)[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyMedicine[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologyskeletal muscle030304 developmental biologyDenervation0303 health scienceslcsh:QP1-981Tissue Engineeringbusiness.industryRegeneration (biology)Editorial ArticleSkeletal musclevasculature nicheBiomaterial3. Good healthmedicine.anatomical_structureTraumatic injuryscaffoldscardiac tissue engineering; regenerative medicine; scaffolds; skeletal muscle; stem cell transplantation; vasculature nichebusinessStem Cell Transplantationdescription
International audience; The generation of engineered tissues and organs has entered into the clinical practice in response to the chronic lack of organ donors. In particular, for the skeletal and cardiac muscles the translational potential of tissue engineering approaches has clearly been shown, even though the construction of these tissues lags behind others given the hierarchical, highly organized architecture of striated muscles. Failure of the cardiac tissue leads to cardiovascular diseases, which are the leading cause of death in the developed world (Di Felice et al., 2014). On the other hand, there are many clinical cases where the loss of skeletal muscle due to a traumatic injury, an aggressive tumor, or prolonged denervation may be cured by the regeneration of the muscle tissue (Perniconi and Coletti, 2014).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-02-01 |