6533b82ffe1ef96bd1295d0d

RESEARCH PRODUCT

Induction of secondary cytotoxic T-lymphocytes in vitro does not require cell proliferation.

Röllinghoff MWagner HOvary Z

subject

Cell divisionCell growthEffectorT-LymphocytesMice Inbred StrainsBiologymedicine.diseaseCytotoxicity Tests ImmunologicGeneral Biochemistry Genetics and Molecular BiologyIn vitroMitomycinsTissue cultureMiceHistocompatibility AntigensImmunologyCancer researchmedicineNeoplasmCytotoxic T cellAnimalsImmunologic MemoryFunction (biology)Cell Division

description

SummaryUsing a mouse in vitro allograft model, evidence has been obtained that, in contrast to the accepted view, the generation of cytotoxic effector function in T-lymphocytes does not necessarily require cell division.

10.3181/00379727-151-39207https://pubmed.ncbi.nlm.nih.gov/1082599