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RESEARCH PRODUCT
D-Glucose as a Pentavalent Chiral Scaffold
Stefan HenkeHorst KunzChristopher KallusTobias WunbergTill OpatzWolfgang Schmidtsubject
Scaffoldchemistry.chemical_compoundSolid-phase synthesisChemistryD-GlucosePeptidomimeticYield (chemistry)Organic ChemistrySide chainStructural diversityOrganic chemistryPhysical and Theoretical ChemistryCombinatorial chemistrydescription
A novel carbohydrate-based scaffold for combinatorial chemistry has been developed. This scaffold allows the selective attachment of five different side chains, giving rise to products of enormous structural diversity. As a demonstration of its usefulness, a series of model compounds has been prepared in high purity and yield by multistep parallel synthesis on a solid phase. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-04-01 | European Journal of Organic Chemistry |