6533b830fe1ef96bd12965cd
RESEARCH PRODUCT
Amino-Acid-Based Polymerizable Surfactants for the Synthesis of Chiral Nanoparticles
Rafael Muñoz-espíRafael Muñoz-espíManfred WagnerKatharina LandfesterLaura PreissYitzhak Mastaisubject
inorganic chemicalsMaterials sciencePolymers and PlasticsPolymersNucleationNanoparticleModel system02 engineering and technology010402 general chemistry01 natural sciencesPolymerizationlaw.inventionSurface-Active AgentsPulmonary surfactantlawMaterials ChemistryOrganic chemistryAmino AcidsCrystallizationchemistry.chemical_classificationMolecular Structureorganic chemicalsOrganic Chemistrytechnology industry and agricultureEnantioselective synthesisStereoisomerism021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical sciencesAmino acidchemistryNanoparticles0210 nano-technologyChirality (chemistry)description
Amino-acid-based chiral surfactants with polymerizable moieties are synthesized, and a versatile approach to prepare particles thereof with a chiral surface functionality is presented. As an example of an application, the synthesized particles are tested for their ability as nucleating agents in the enantioselective crystallization of amino acid conglomerate systems, taking rac-asparagine as a model system. Particles resulting from chiral surfactants with different tail groups are compared and the results demonstrate that only the chiral nanoparticles made of the polymerizable surfactant are able to act efficiently as nucleation agent in enantioselective crystallization.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-04-08 | Macromolecular Rapid Communications |