6533b830fe1ef96bd1296ed5

RESEARCH PRODUCT

Rearranged abietane diterpenoids from the root of teucrium polium subsp. vincentinum

Marfa C. De La TorreMaria C. CarreirasAurea PeralesMaria R. TorresBenjamín RodríguezFranco PiozziGiuseppe Savona

subject

chemistry.chemical_compoundfoodChemistryStereochemistryChemical structureOrganic ChemistryDrug DiscoveryDiterpeneBiochemistryTeucrium poliumfood.foodAbietaneCyclopropane

description

Abstract From the root of Teucrium polium subsp. vincentinum (Labiatae) four new rearranged abietane derivatives, teuvincenones A, B, C, and D (1-4, respectively), have been isolated. Two of these compounds, teuvincenones C (3) and D (4), possess a novel hydrocarbon skeleton which contains a cyclopropane ring constituted by the C-3, C-4, and C-18 carbons of the 17(15→16)-abeo-abietane framework. The structures of these diterpenoids were established mainly by spectroscopic means and, in the case of teuvincenones A (1) and C (3), also confirmed by X-ray diffraction analyses.

https://doi.org/10.1016/s0040-4020(01)81367-3