6533b830fe1ef96bd1296ef2
RESEARCH PRODUCT
Synthesis and Chemical Reactivity of 5-Methoxy-2-vinyl-4-azaindoles
José Sepúlveda-arquesE. Gonzalez-rosendeElena Zaballos-garcíaMohamed Djebouri SidiL. Rodriguez-salvadorR. A. Jonessubject
Dimethyl acetylenedicarboxylatechemistry.chemical_compoundchemistryYield (chemistry)Organic Chemistrytechnology industry and agricultureOrganic chemistryDerivative (chemistry)Adductdescription
Abstract 2-Vinyl-4-azaindoles are less reactive with dienophiles than 2-vinylindoles. 5-Methoxy-2-vinyl-4-azaindole 2a and its 1-methyl derivative 2a reacts with N-phenylmaleimide to yield cycloadducts only under vigorous conditions. 2b produces a cycloadduct with dimethyl acetylenedicarboxylate, while 2a yields a Michael-type adduct. Reactions with more reactive dienophiles gave only polymeric products.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-04-01 | Synthetic Communications |