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RESEARCH PRODUCT

Intracytoplasmic Testicular Sperm Injection: An Effective Treatment for Otherwise Intractable Obstructive Azoospermia

Manuel Gil-salomJosé RemohíAntonio PellicerCarmen RubioYolanda Minguez

subject

GynecologyAzoospermiaendocrine systemmedicine.medical_specialtyPregnancyurogenital systembusiness.industryUrologymedicine.medical_treatmentUrologyObstructive azoospermiaTesticleurologic and male genital diseasesmedicine.diseaseIntracytoplasmic sperm injectionTesticular sperm extractionPregnancy rateHuman fertilizationmedicine.anatomical_structuremedicinebusinessreproductive and urinary physiology

description

AbstractPurpose: We evaluated the efficacy of intracytoplasmic sperm injection with testicular spermatozoa.Materials and Methods: Intracytoplasmic sperm injection was performed with spermatozoa obtained from testicular biopsy specimens in 15 patients with obstructive azoospermia, in whom standard microsurgical procedures were not feasible or had previously failed.Results: Fertilization was achieved in 14 to 15 cycles. Mean fertilization rate per cycle was 63.6 percent. Four clinical pregnancies occurred, for a pregnancy rate of 26.7 percent per started cycle and 28.6 percent per transfer.Conclusions: Intracytoplasmic testicular sperm injection is followed by high fertilization rates, and offers the chance of a pregnancy to otherwise intractably infertile couples with obstructive azoospermia.

yearjournalcountryeditionlanguage
1995-12-01Journal of Urology
https://doi.org/10.1016/s0022-5347(01)66698-9