6533b830fe1ef96bd12979cc

RESEARCH PRODUCT

Acquired and Hereditary Angioedema: Pathogenesis and Therapy

K. Bork

subject

Angioedemabusiness.industryfood and beveragesMast cellmedicine.diseasePathogenesischemistry.chemical_compoundmedicine.anatomical_structurechemistryimmune system diseasesImmunologyHereditary angioedemamedicineAntihistaminic drugscardiovascular diseasesmedicine.symptomskin and connective tissue diseasesbusinessHistamine

description

There are two main pathogenetic ways by which angioedema can develop. These pathways are completely different and lead to completely different diseases, which may have angioedema of the skin in common. Most cases of cutaneous angioedema develop with involvement of the mast cell and its mediators; especially histamine is considered to play a major role. The exact pathogenesis, however, is not known. This type of angioedema is assumed to be related to urticaria for several reasons: 1 Often it appears alternately with urticaria 2 It responds to antihistaminic drugs 3 The same causes may provoke either urticaria or angioedema

yearjournalcountryeditionlanguage
1988-01-01
https://doi.org/10.1007/978-3-642-83360-1_14