6533b830fe1ef96bd1297bdb
RESEARCH PRODUCT
Regiospecific and stereoselective ene reaction of the A-ring methylcyclohexene moiety of polycyclic terpenoid systems with dimethyl acetylenedicarboxylate
Consuelo AgullóAna C. CuñatAntonio AbadCarmen Ramírez De ArellanoIsmael Navarrosubject
Dimethyl acetylenedicarboxylatechemistry.chemical_compoundchemistryMoietyStereoselectivityGeneral ChemistryRing (chemistry)Medicinal chemistryEne reactionTerpenoiddescription
Polycyclic terpenoid compounds with a methylcyclohexene moiety at the A-ring, such as 1 and 7, give a regio- and stereoselective ene reaction when heated at low temperatures with dimethyl acetylenedicarboxylate. The structure and stereochemistry of the compound formed in the case of 1, e.g. 5, is determined by X-ray analysis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-03-01 |